|The NEMO Project investigates the interplay between political governance, structure and function of politically induced R&D collaboration networks, in particular the networks that have emerged in the European Framework Programmes. The ultimate goal is to identify ways to create and to appraise desirable ('optimal') network structures for typical functions of such R&D collaboration networks (e.g. knowledge creation, transfer and (distribution). This will aid policymakers at all political levels in improving the effectiveness and efficiency of network-based policy instruments at promoting the knowledge economy in Europe. Assembling leading researchers from mathematics, physics, economics and sociology in a single project, we will explore modelling strategies to create new theoretical frameworks, building blocks and classes of models. To this end, solid mathematical foundations will be provided for the class of models developed in this project. Theoretical results will be validated via two comprehensive empirical data sets and networks generated by multi-agent simulation. The empirical analyses will yield detailed knowledge on the structural properties of the R&D collaboration networks that have emerged in the EU Framework Programmes. Desirable network structures will be identified and new quantitative methods for evaluating the governance of network based instruments will be developed.